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Pathology of Shock

Shock Definition : Shock is a life threatening clinical syndrome of cardiovascular collapse characterised by hypotension and hypoperfusion. Classification : 1.       Hypovolaemic shock : This is occur due to circulatory blood volume. 2.       Cardiogenic shock : Acute circulatory failure with sudden fall in cardiac output. 3.       Septic shock : It is occur due to severe bacterial infection. 4.       Other types : Traumatic shock, Neurogenic shock and Hypoadrenal shock. Pathogenesis : ·          Reduced effective circulating blood volume. ·          Impaired tissue oxygenation. ·          Release of inflammatory mediators. Morphological features : The morphologic changes in shock are due to hypoxia resulting in degeneration and necrosis of various organs like brain, heart, lungs and kidneys. Clinical features : Very low blood pressure, subnormal temperature, feeble and irregular pulse, shallow and sighing respiration, pale face, sunken eyes, w

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Textbook Of Physiology By K Sembulingam PDF

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