Medical Study point

Chalcosis oculi (Greek chalkos: copper): Chronic ophthalmic exposure to particulate elemental copper or one of its alloys may result in its deposition in the cornea, lens, vitreous and retina. Copper deposits in the cornea (chalcosis corneae) appear as golden brown, ruby red or green pigment ring in the peripheral Descemet's membrane (Kayser Fleischer ring). Lens opacities (chalcosis lentis) occur in the form of anterior subcapsular cataract ('sunflower' cataract and typically greenish in color).

Ochronosis:-  ochronosis is the bluish black discoloration of tissues, such as the ear cartilage and the ocular tissue (sclera, between the margin of the cornea and the outer or inner canthus), seen with alkaptonuria (autosomal recessive metabolic disorder caused by deficiency of homogentisic acid oxidase). It can also occur from exposure to various substances, such as phenol, trinitrophenol, resorcinol, mercury, picric acid, benzene, hydroquinone and antimalarials.